INTODUCTION TO GENERAL PATHOLOGY-branches of general pathology, etiology and pathogenesis -homeostasis and diseases
ETIOLOGY
-causes of diseases
-classification of etiological agents
-the host-etiological agent interaction
GENETIC DISEASES
-mutations
-effects of the mutation on somatic and germ cells
-classification of mutations
-gene mutations and consequences: albinism
-genetic diseases of hemoglobin
-description of hemoglobin proteins and genes
-classification of beta thalassemia
-molecular bases of beta thalassemia
-relationship between genetic background and clinical manifestations -pathogenetic mechanisms of beta thalassemia major
-siderosis
-examples of chromosomal aberrations and related diseases
-pathogenesis and examples of aneuploidies and mosaicisms
-trisomy 21
HEAT-RELATED DISEASES
-main features of heat transfer
-classification and pathogenesis of burns
-systemic effects of burns
RADIATION-RELATED DISEASES
-definition and classification of the radiations
-radioisotope
-effects of radiation on atoms and molecules
-effects of radiation on cells
-effects of radiations on tissues and organs
CHEMICALS-RELATED DISEASES
-classification of chemicals: distribution in the natural and work environments
-air pollution: example of related diseases
-soil and water pollution: example of related diseases
-professional diseases: examples
-smoking-related diseases
-alcohol abuse-related diseases
INFECTIOUS DISEASES
-worldwide distribution of infectious diseases
-microorganisms, antibiotics and resistances
-types of infections
-microorganism/host interaction
-main types of pathogenic microorganisms
-pathogenesis of infectious diseases: toxigenic, invasion, virulence
-main features of infectious diseases
-classification and main features of toxins
-endotoxins, septic shock
-exotoxins: examples of associated diseases
INFLAMMATION
-main features of defensive reactions
-definition and examples of inflammatory agents
-distinctive features of acute and chronic inflammation
-symptoms and phases of inflammation
-histamine
-mechanisms of generation of inflammatory exudate
-wound healing
-cells of inflammation
-diapedesis
-bactericidal mechanisms in inflammation
-molecular mediators of inflammation
-clinical classification of the inflammatory exudates
-chronic inflammation
-structure and cells of the granuloma
IMMUNITY
-types of immune response: natural, acquired, active, passive, humoral, cell-mediated, primary, secondary
-phases of the immune response
-clonal selection
-antigens: main structural features
-antibodies: classification, structure and function
-cell mediated immunity
-antigen presenting cells
-antigen presentation
ONCOLOGY
-majors of epidemiology, etiology and nomenclature
-benign tumors and malignant cancers
-main features of cancer cells
-neoplastic transformation-invasiveness and metastatization
-tumor neovascularization