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The Course is composed by a part of Internal Medicine competence and by a more specific part of Endocrine and Metabolic diseases competence. At the end of the course the student should demonstrate a systematic knowledge of the most important diseases of different apparatuses and the ability to critically evaluate clinical symptoms and signs, in relationship with etiology, functional alterations and anatomo-pathological lesions. He/she should also be able to perform a proper diagnostic process and to deal specifically with complex problems which cross different pathological entities.