To know the embryology, anatomy and physiology of the structures of the splanchnocranium and, in particular, of the oral cavity, of the teeth and of the constituents of the stomatognathic apparatus; To know the ecosystem of the oral cavity and, in particular, the microorganisms of the mucobacterial plaque and their cariogenic role; To know the mechanisms of inflammation (angioflogosis and histoplogosis) and of the local and systemic immune response; To know the fundamentals of inorganic chemistry: chemical bonds, solutions, oxidation-reduction, acids and bases and of inorganic and biomolecular chemistry. Know the physical-chemical characteristics, the products and the methods of use and conservation, in line with the directives and international standards, of the dental materials used in the endodontic treatment; Knowing the fundamentals of Mechanics, Dynamics, Thermodynamics, Rheology, Optics, Electrophysics, Radiation Physics, Radioprotection and Radiographic Techniques; Know the principles of prophylaxis of infectious diseases and cross-infection, disinfection and ergomomic sterilization of instruments; Know the principles of Pharmacology and Anesthesiology. Know the principles of Clinical Medical and Surgical