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1 credits - Language/Final Examination

BIOCHEMISTRY

Single discipline educational activity

Course Sheet

Academic Year of enrolment:

2017/2018

Academic Year of provision:

2017/2018

Type of Course:

Basic

Degree:

Bachelor's Degree Programme in MIDWIFERY

Disciplinary Sector:

Biochemistry

Language:

Italian

Grouping head:

BIOMOLECULAR AND PROPEDEUTIC SCIENCES

Grouping type:

Credits:

Programme Year:

Professor and Collaborators:

MITOLA Stefania Maria Filomena Professor

Cycle:

First semester

Hours of classroom activity:

Hours of individual study:

knowledge of basic chemistry

Educational Goals

The aim of the course is to provide the knowledge of the general biochemistry in order to understand the structure and function of the macromolecules of biological interest, the mechanisms of metabolic activities and their regulation.

Content

METABOLISM
General and Basic concepts - Catabolism of macromolecules - Catabolism as a source of energy - Metabolism of the main organs
ENZYMES
Chemical nature - Speed of enzymatic reactions - Mechanisms of action. Regulation
GLUCID METABOLISM
Main carbohydrates (monosaccharides, disaccharides, polysaccharides) - Structural and biological function of carbohydrates - Glycogenosynthesis and glycogenolysis - Glycolysis - Krebs cycle - Oxidative phosphorylation -
LIPID METABOLISM
Classification of lipids - Functions and properties - Biosynthesis and catabolism of fatty acids - Cholesterol biosynthesis - Ketogenesis - Lipoproteins
PROTEIN METABOLISM
Amino acids and peptide bond - Protein structure - Function and properties of proteins - Collagen structure, hemoglobin and myoglobin

Extended Syllabus

Digestion and absorption of carbohydrates. Glycolysis. Lactic and alcoholic fermentations.
Glycogenolysis.
Regulation of glycolysis and glycogenolysis.
Signaling pathways: membrane receptors and signal transduction.
Energy balance from glucose in anaerobic and aerobic conditions.
Glucose (gluconeogenesis) and glycogen synthesis . Their regulation.
- Pyruvic dehydrogenase. Krebs cycle and its regulation.
The mitochondrial respiratory chain. Oxidative phosphorylation.
- Digestion and absorption of lipids. Catabolism of triglycerides in adipose tissue. Catabolism of fatty acids: b-oxidation and its regulation. Synthesis of fatty acids and its regulation. Triglyceride synthesis and its regulation.
- Digestion of proteins and absorption. Urea cycle and its regulation. Glucogenic, ketogenic, glucogenic / ketogenic amino acids.
Essential and non-essential amino acids.

Recommended Bibliography

Ferrier Le basi della biochimica Zanichelli
Cantoni Appunti di biochimica , Piccin

Methods of Provision

Conventional

Teaching Methods

frontal lessons

Assessment Methods

student must demonstrate his/her knowledge of the metabolic mechanisms through a written test with open questions.

Assessment:

Final Mark

Programme of Educational Activities

Start date of teaching period:

Monday, October 2, 2017

End date of teaching period:

Friday, January 26, 2018

Amministrazione trasparente

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