-Summary and Synthesis of the regulation mechanisms of spatio-temporal gene expression in the development of the zygote in newborn and adult organisms and in the processes of differentiation
-Knowledge of the experiment by Gurdon and of the experiment of the Dolly sheep
-Mechanisms of gene expression regulation mediated by microRNA and DNA methylation
-Concepts of genetic and epigenetic inheritance
- Knowledge of the biological and genetic bases of tooth development
- Knowledge of the structure and function, formation process of extracellular matrices present in the tooth: dentin and enamel
-Biology of stem cells, embryonic and adult, and biology of induced pluripotent stem cells (iPSC)
-Regenerative medicine for tooth tissue engineering
-Knowledge of the clinical characteristics and of the molecular defect of some genetic diseases that affect the tooth: hypodontia, anhidrotic ectodermal dysplasia, dentinogenesis imperfecta associated with osteogenesis, dentinogenesis imperfecta without osteogenesis imperfecta, amelogenesis imperfecta.
- integration of the topics illustrated and provided during the whole integrated course in Applied Biology consisting of three modules, Applied Biology I, General and Molecular Genetics. Biology and Applied Genetics at Dentistry.