Portale di Ateneo - En.Unibs.it

General principles of Pharmacology: origin and nature of drugs, pharmaceutical forms, the prescription, the pharmaceutical prescription in dentistry, the development of new drugs.Pharmacokinetics: routes of administration, absorption and distribution, bioavailability, metabolism, excretion. -Pharmacodynamics: receptors, mechanism of action of drugs, antagonist agonists, dose-response relationship, therapeutic index, potency, efficacy. -Factors that influence the response to drugs: factors inherent to the drug, factors inherent to the patient, drug interactions.Adverse drug reactions: classification, overdose, drug intolerance, fetal toxicity and teratogenesis, pharmacovigilance.Pharmacology of the autonomic nervous system: parasympathetic nervous system and cholinergic transmission, direct and indirect cholinergic drugs, drugs of the autonomic nervous system and salivation; sympathetic nervous system and adrenergic transmission, direct and indirect adrenergic agonist drugs and antagonists. Cardiovascular system pharmacology: hypertension therapy, central and peripheral sympatholytic drugs, calcium antagonists, direct vasodilators, renin-angiotensin-aldosterone system drugs, diuretics. Outlines arrhythmia therapy and heart failure. Coagulation drugs: antiplatelet, anticoagulants, fibrinolytics, antihaemorrhagics. Shock therapy.Drugs for diabetes therapyDrugs for the treatment of dyslipidemiaAnalgesics and anti-inflammatories: principles and mechanisms of inflammation, NSAIDs, use of NSAIDs in dentistry. Steroidal anti-inflammatories, synthetic glucocorticoids, side effects, use of glucocorticoids in dentistry. - Central analgesics: neuronal mechanisms of nociceptive transmission, opioid peptides, natural, semi-synthetic and opioid opioids, opioid receptor antagonists, opioids in dentistry.Antihistamine drugs: histamine and receptor antagonists H1 and H2. Antiulcer drugs and antiemetic drugs.CNS drugs, anxiety and insomnia therapy, anxiolytic and sedative drugs, benzodiazepines and non-antidepressants and mood stabilizers, antiepileptics, antipsychotics, General anesthesia medications: pre-anesthetic medication, balanced anesthesia, intravenous anesthetics and inhalers, neuromuscular blockers - Local anesthesia drugs: pharmacological activity, clinical use, undesirable effects, hypersensitivity reactions.Pharmacology of movement disorders, Parkinson's disease therapy. Central muscle relaxants, direct muscle relaxants and therapy of the mandibular skull syndromesDrugs active on bone metabolism: bone tissue physiology, calcium homeostasis, osteoporosis and oral osteopenia, pharmacological therapy.Antimicrobial chemotherapies for dental use: dental infectious pathology, mechanism of action of antibacterial agents, bacterial resistance, selection criteria of antibiotics, beta-lactams, macrolides, lincosamines, tetracyclines, metronidazole, fluoroquinolones, chemoprophylaxis in dentistry. Antivirals and antifungals.Antiseptics and disinfectants: general mechanism of action, classification, protocol of antisepsis and disinfection.